The GB Special Olympics team is joining around 2,000 competitors in the European Summer Games in Antwerp, Belgium, to go head-to-head across ten sports.
Hosting a reception for the athletes in the garden at No 10, the Prime Minister said the games would help to change attitudes towards intellectual disabilities.
Mr Cameron said it was good that participants from across the UK were taking part. The Special Olympics organises the summer games every four years, attracting thousands of athletes to compete in sports such as athletics, gymnastics, football, cycling, judo, table tennis and swimming.
Sheffield was confirmed earlier this summer as the host city for the next games in 2017.
Deputy Prime Minister Nick Clegg said: “The next special games here in the UK will be held 2017 in Sheffield. I’m an MP from Sheffield and I’m absolutely delighted that you will be competing, at least many of you I hope will be competing in 2017.”
“We have got a fantastic set of sporting facilities and you’ll get a very, very warm welcome in 2017.”